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HIGH RATE OF DEPRESSION IN PATIENTS WITH CHRONIC HEPATITIS C

Authors

Max Kopti Fakoury Universidade Federal do Estado do Rio de Janeiro (UNIRIO) https://orcid.org/0000-0002-7003-9942
Catherine da Cal Valdez Ximenes UNIRIO
Marcia Amendola Pires UNIRIO
Aureo Carm o Filho UNIRIO https://orcid.org/0000-0001-6599-4358
Alan Messala A. Brito UNIRIO https://orcid.org/0000-0002-3871-8064
Carlos Eduardo Brandão Mello UNIRIO

DOI:

https://doi.org/10.9789/2175-5361.rpcfo.v13.11384

Keywords:

Chronic Hepatitis C, depression, DSM-V, hepatitis C

Abstract

Objectives: To describe the frequency of depression in patients with hepatitis C (HCV) and relate to the biological variables and liver function.

Methods: Cross-sectional, descriptive study with a quantitative approach, which assessed depression using the criteria of the Diagnostic and Statistical Manual of Mental Disorders (DSM-V) and the association with biological and liver function variables in 85 patients HCV chronically infected indicated for direct-acting antiviral therapy (DAA) between May 2018 and May 2019.

Results: Depression was detected in 47.1% of patients, predominantly mild depression (95%). However, depression occurred independently of biological characteristics, such as gender, age, education, associated comorbidities and liver function, such as degree of fibrosis and viral genotype.

Conclusions: The frequency of depression was high in patients with HCV and had no statistical relationship with biological characteristics and liver function, suggesting that active search for depression could be a valuable strategy in managing these patients.

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Author Biographies

Max Kopti Fakoury, Universidade Federal do Estado do Rio de Janeiro (UNIRIO)

Médico. Professor de Clínica Médica e Geriatria do Departamento de Medicina Geral da Universidade Federtal do estado do Rio de Janeiro - UNIRIO

Catherine da Cal Valdez Ximenes, UNIRIO

Postgraduate Program in HIV/AIDS and Viral Hepatitis, PPGHIV/HV-UNIRIO, Federal University of the State of Rio de Janeiro, RJ, Brazil

Marcia Amendola Pires, UNIRIO

Postgraduate Program in Neurology, Department of Neurology, PPGNEURO -UNIRIO, Federal University of the State of Rio de Janeiro, RJ, Brazil

Aureo Carm o Filho, UNIRIO

Postgraduate Program in Neurology, Department of Neurology, PPGNEURO -UNIRIO, Federal University of the State of Rio de Janeiro, RJ, Brazil

Alan Messala A. Brito, UNIRIO

Oncovirology Program of the National Cancer Institute, INCA, RJ, Brazil

Division of Nursing, Gaffrée and Guinle University Hospital, Federal University of the State of Rio de Janeiro, RJ, Brazil

Department of Genetics, Health Sciences Center, Federal University of Rio de Janeiro, Brazil

Carlos Eduardo Brandão Mello, UNIRIO

Department of Internal Medicine, Gaffrée and Guinle University Hospital, Federal University of the State of Rio de Janeiro, RJ, Brazil

Postgraduate Program in Neurology, Department of Neurology, PPGNEURO -UNIRIO, Federal University of the State of Rio de Janeiro, RJ, Brazil

Postgraduate Program in HIV/AIDS and Viral Hepatitis, PPGHIV/HV-UNIRIO, Federal University of the State of Rio de Janeiro, RJ, Brazil

References

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Published

2021-09-28 — Updated on 2021-09-28

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Fakoury MK, Ximenes C da CV, Pires MA, o Filho AC, Brito AMA, Mello CEB. HIGH RATE OF DEPRESSION IN PATIENTS WITH CHRONIC HEPATITIS C. Rev. Pesqui. (Univ. Fed. Estado Rio J., Online) [Internet]. 2021Sep.28 [cited 2024May17];13:1442-6. Available from: https://seer.unirio.br/cuidadofundamental/article/view/11384

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</div>

HIGH RATE OF DEPRESSION IN PATIENTS WITH CHRONIC HEPATITIS C

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DOI:

Keywords:

Abstract

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Author Biographies

Max Kopti Fakoury, Universidade Federal do Estado do Rio de Janeiro (UNIRIO)

Catherine da Cal Valdez Ximenes, UNIRIO

Marcia Amendola Pires, UNIRIO

Aureo Carm o Filho, UNIRIO

Alan Messala A. Brito, UNIRIO

Carlos Eduardo Brandão Mello, UNIRIO

References

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